CAR-T cells can arm bystander T cells with CAR molecules in tumor microenvironment
Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now ...
Nature4y
CRISPR expands CAR T cell possibilities
As interest in immunotherapy grows, so does the need for better tools to engineer CAR T cells ... and function of human T cells without the need for viral vectors 6. This study demonstrated ...
The Scientist5d
Inducible CAR T Cells Target Solid Tumors Better
Researchers at Cellectis leveraged gene editing to create a CAR T cell that acts in an IF/THEN system. Traditional methods to develop CAR T cells that use the patient’s cells introduce challenges ...
Hackaday4mon
Using Donor Immune Cells To Mass-Produce CAR-T Autoimmune Therapies
After injection, the CAR-T cells got to work ... which persisted at 6 months. For the woman with IMNM, muscle strength had increased dramatically with undetectable autoantibody levels, and ...
News Medical27d
New drug cocktail enhances CAR-T cells for cancer treatment
This finding may have a significant impact on improving the production of CAR-T cells for clinical use. CAR-T cell immunotherapy involves harvesting immune-system T cells from a patient and ...
Medical Xpress1mon
A battle of rafts: How molecular dynamics in CAR T cells explain their cancer-killing behavior
A study published in Science Advances shares new insights into how two of the most common types of chimeric antigen receptor (CAR) T cells kill cancer. Investigators from Baylor College of ...
Medical Xpress on MSN8d
New findings could make off-the-shelf CAR T cell therapy a reality
CAR T cell therapy is one of the most promising new cancer treatments to emerge in recent years. It involves removing a patient's own immune T cells and engineering them to recognize specific targets ...