Cellular senescence, where cells permanently stop dividing, plays a complex role in liver health. In a recent review article, ...

Cellular senescence is crucial in processes like ... particularly in macrophages and endothelial cells (ECs), but not in hepatocytes. Flow cytometry and immunostaining further validated that ...

Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively kill these cells or inhibit the secretion of substances is ongoing.

A new research paper was published in Aging (listed by MEDLINE/PubMed as “Aging (Albany NY)” and “Aging-US” by Web of Science ...

The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological significance have been reviewed.

Senescence is the process by which cells irreversibly stop dividing and enter a state of permanent growth arrest without undergoing cell death. Senescence can be induced by unrepaired DNA damage ...

Dr Raimondi’s group focuses on identifying and investigating the signalling pathways regulating cellular senescence, oxidative stress and mitochondria homeostasis in endothelial cells and their ...

Our results suggest that increased Arg-II in non-skeletal muscle cells promotes age-associated sarcopenia, particularly in male mice."BUFFALO, NY ...