Moreover, a band of approximately 90-kD that corresponds to these complexes was observed with a low intensity in the p53 Western blot from lung cancer samples in comparison with the other groups.

A team from University Hospitals Seidman Cancer Center is launching the nation's first-ever clinical trials evaluating the ...

The ATM gene (mutated in the disease ataxia telangiectasia) activates the p53 tumor suppressor protein in response to DNA damage, explaining the higher incidence of cancer in AT patients.

Western blot assays were performed to identify the presence of p53, phospho-p53, and murine double minute 2 (MDM2) isoforms in plasma samples. Densitometric analysis was used to determine the ...